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John Wayne Casserole

Posted on June 3, 2025
Here’s a hearty, crowd-pleasing John Wayne Casserole recipe — packed with seasoned ground beef, cheese, and a biscuit base. It’s classic comfort food with a southwestern twist.


🍲 John Wayne Casserole Recipe

Servings: 6–8
Prep time: 20 mins
Cook time: 30–40 mins
Total time: ~1 hour


✅ Ingredients:

  • Base Layer:

    • 1 (16 oz) can refrigerated biscuit dough (or homemade biscuit mix)

  • Beef Layer:

    • 1 lb ground beef

    • 1 packet taco seasoning (or homemade: cumin, chili powder, paprika, garlic powder)

    • ½ cup water

  • Vegetable & Flavor Layer:

    • 1 medium onion, diced

    • 1 green bell pepper, diced

    • 1–2 tomatoes, diced (or 1 can Rotel, drained)

    • 1 cup sour cream

    • ½ cup mayonnaise

    • 2 cups shredded cheddar cheese (divided)

    • 1 (4 oz) can diced green chilies (optional but authentic)

    • Salt & pepper to taste


🔪 Instructions:

  1. Preheat Oven:
    Preheat your oven to 350°F (175°C). Grease a 9×13-inch baking dish.

  2. Prepare the Base:
    Press biscuit dough into the bottom of the dish to form a flat crust. Bake for 8–10 minutes (just until starting to set, not fully cooked).

  3. Cook the Meat:
    In a large skillet, brown the ground beef. Drain fat, add taco seasoning and water, and simmer until thickened (about 5 minutes).

  4. Sauté Vegetables:
    In the same skillet (or separate), cook onions and bell peppers until softened. Add tomatoes (or Rotel) and green chilies if using. Mix into the seasoned beef.

  5. Mix the Cream Layer:
    In a bowl, combine sour cream, mayonnaise, and 1 cup of the shredded cheese.

  6. Assemble the Casserole:

    • Spread the beef and veggie mixture over the biscuit crust.

    • Spread the sour cream mixture over the top of the beef.

    • Sprinkle remaining 1 cup of cheese over everything.

  7. Bake:
    Bake uncovered for 30–35 minutes, until cheese is bubbly and starting to brown.

  8. Serve:
    Let cool for 5–10 minutes before serving. Garnish with chopped green onions, jalapeños, or cilantro if desired.


🔄 Variations:

  • Spicy: Add sliced jalapeños or hot sauce to the meat mixture.

  • Lower carb: Skip the biscuit crust and bake it as a crustless casserole.

  • Tex-Mex flair: Use pepper jack cheese or add black beans and corn.

Let me know if you’d like a version with chicken or a gluten-free option!

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